Resources
External Tools & Resources
A curated hub of tools, databases, and repositories used alongside the ImmuneVISTA platform for multi-omic systems immunology and vaccine research.
Immunology
Immune-focused datasets, epitopes, and reference expression.
ImmPort
↗A sustainable, publicly accessible archive of immunology data generated by NIAID/DAIT investigators.
IEDB
↗The Immune Epitope Database: curated B-cell and T-cell epitope data and prediction tools.
DICE
↗Database of Immune Cell Expression, expression quantitative trait loci, and epigenomics.
MSigDB
↗Molecular Signatures Database, including blood transcription modules widely used in systems vaccinology.
ImmuneSpace / HIPC
↗Systems-immunology datasets and analysis tools from the Human Immunology Project Consortium (HIPC).
Multi-Omic Databases
Reference resources spanning transcriptomics, proteomics, and metabolomics.
NCBI GEO
↗Gene Expression Omnibus: a public functional genomics data repository and ImmuneVISTA deposition target.
Ensembl
↗A genome browser for vertebrate genomes supporting comparative genomics, variation, and regulation.
UniProt
↗Comprehensive, high-quality protein sequence and functional annotation resource.
Metabolomics Workbench
↗A repository and analysis platform for metabolomics data, protocols, and reference standards.
HMDB
↗The Human Metabolome Database: detailed chemical, clinical, and biochemical metabolite data.
GTEx
↗Tissue-specific gene expression and regulation reference across the human body.
Pathways & Networks
Pathway, enrichment, and interaction-network analysis.
KEGG
↗A database for understanding high-level functions and pathways from large-scale molecular datasets.
Reactome
↗An open-source, manually curated and peer-reviewed pathway database.
Gene Ontology
↗Standardized, structured annotation of gene and gene-product function across species.
STRING
↗Protein–protein interaction networks with functional enrichment analysis.
Enrichr
↗Gene-set enrichment analysis across an extensive collection of annotated libraries.
g:Profiler
↗Functional enrichment analysis and gene identifier conversion.
Analysis Tools
Software, pipelines, and environments for reproducible analysis.
Bioconductor
↗R/Bioconductor packages for genomic, transcriptomic, and multi-omic data analysis.
BioGrids
↗A project of the SBGrid Consortium that simplifies installing and managing life-sciences software.
MetaboAnalyst
↗Statistical, functional, and pathway analysis tailored to metabolomics data.
nf-core / Nextflow
↗Community-curated, portable, and reproducible bioinformatics pipelines.
REDCap
↗A secure web application for online and offline research data capture.
Data Repositories & Standards
Deposition targets, registries, and data standards.
ProteomeXchange / PRIDE
↗Standardized proteomics data deposition and a public repository of mass-spectrometry data.
ClinicalTrials.gov
↗Registry and results database of publicly and privately supported clinical studies.
FAIRsharing
↗A curated registry of data standards, databases, and policies supporting FAIR data.