What the DMAC Provides
Capabilities & Standards
The Data Management and Analysis Core provides end-to-end data and bioinformatic infrastructure for systems immunology studies — from sample intake through reproducible analysis and public deposition — under a rigorous data governance framework.
Core Services
Sample & Metadata Management
Structured tracking of biological samples and study metadata across collaborating sites, with consistent identifiers and provenance from collection through analysis.
Two-Tier Quality Control
Quality control at the generating institution followed by independent DMAC validation before any dataset enters the platform — assay-aware checks for omic data types.
Multi-Omic Integration
Harmonization of transcriptomic, proteomic, metabolomic, and cytokine/chemokine data into analysis-ready resources for systems immunology research.
Reproducible Analysis Environments
Managed RStudio Server Pro environments on a cloud architecture so analyses are versioned, shareable, and reproducible across studies and team members.
Study Design Support
Reproducible randomization and power/sample-size analysis to support rigorous, well-powered study designs and transparent allocation.
Data Deposition
Publication of analyzed, de-identified datasets to public repositories including ImmPort and Gene Expression Omnibus, supporting open science mandates.
Data Governance & Standards
How we keep research data rigorous, secure, and trustworthy.
NIH Data Standards
Data are tracked, stored, and shared in accordance with National Institutes of Health data management and sharing expectations.
De-Identification & Privacy
Only de-identified data enter the platform. Sample-level and identifiable information are handled under institutional governance and never exposed publicly.
Secure Cloud Architecture
Infrastructure is built on Amazon Web Services with access controls appropriate to research data, separating public-facing content from protected datasets.
FAIR & Reproducibility
Workflows emphasize Findable, Accessible, Interoperable, and Reusable data, with versioned analysis environments so results can be independently reproduced.
Bring your study to ImmuneVISTA
The DMAC partners with investigators and consortia to manage, analyze, and share multi-omic data with rigor and reproducibility.